Evaluación de la resiliencia al cáncer y al envejecimiento en adultos mayores con neoplasias hematológicas: el registro CARE-Heme

ID de estudio #: NCT05556928

condición: Multiple Myeloma, Amyloidosis, Plasma Cell Leukemia

Estado: Reclutamiento

The primary purpose of this protocol is to create a registry of older (≥50 years old) patients with Hematologic Malignancies. Our main objectives include: To understand the prevalence of frailty and geriatric impairments among patients aged ≥50y and above diagnosed with a hematologic malignancy at UAB and to gather information that would lend support for future research in this vulnerable population.

Resultados: https://clinicaltrials.gov/ct2/show/results/NCT05556928

última actualización: Febrero 22, 2024

fecha de inicio: 21 de Julio de 2020

finalización estimada: 31 de diciembre de 2024

última actualización: Febrero 20, 2024

tamaño / inscripción: 5000

descripción del estudio: All participants will be invited to participate in a patient reported geriatric assessment questionnaire as well as an objective physical function testing. This includes the Short Physical Performance Battery (SPPB) that evaluates lower extremity performance and muscle strength assessment via hand grip dynamometer. Participants will also complete a 12 item modified version of PRO-CTCAE. This will be administered by trained research staff at the time of study enrollment. Repeat CARE instruments (Follow-up GA questionnaire and Physical Function test) will be administered after the baseline visit to measure changes in patient reported outcomes at 3 months, 6 months, and one year. A one-time blood or saliva sample will be requested and obtained at baseline or a follow-up visit.

resultados primarios:

• Create the CARE-Heme Registry
  To establish and maintain a well-annotated registry (to be called the 'CARE-Heme' Registry) of adults ≥50 years of age with a hematologic malignancy to improve our understanding of this vulnerable population.
• 5 años
  

resultados secundarios:

• To administer a patient reported geriatric assessment and a brief objective physical assessment.
  5 años

criterios de inclusión:

Criterio de exclusión: Criterios:

Individuals who are <50 years old.
Patients who do not read and/or speak English will not be eligible for this study as many of the questionnaires are not validated in other languages. No exclusions will be made based on gender, ethnicity or race.

patrocinador: Universidad de Alabama en Birmingham

Contactos: Smith Giri, Dr., (205) 638-2120, GME@dhr-rgv.com

ubicaciones del centro de prueba: Estados Unidos

• Estados Unidos, Alabama
  Clínica Kirklin del Hospital UAB
  Smith Giri, Dr., 205-638-2120, GME@dhr-rgv.com